Histopathologic findings in naturally preserved mummified human eyes.

cells with less fluorescent nuclei. The corneal epithelial cellular autofluorescence was most likely due to nicotinamide adenine dinucleotide phosphate. At 200 μm, the collagen pattern at the wound is irregularly arranged, which is in sharp contrast to the orthogonal packing of adjacent lamella found in normal stroma (Figure 1H). At imaging depths of 400 μm and beyond, regions lacking in SHG collagen were observed. In addition, the collagen fibers outside of the wound tended to align parallel to the wound edges. At the imaging depths of 1000 and 1200 μm, intense fluorescent lining (possibly from detached uveal tissue) along the wound edge was found (Figure 1I). For comparison, the histological image is shown in Figure 2. Both the surface epithelial cells and the V-shaped corneal wound were visible. At greater depths, we also found granulation tissue (with cells). The existence of the corneal wound and granulation tissue may explain the lack of SHG collagen fibers within the wound.